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Improving the photosensitization efficiency represents a critical challenge in photodynamic therapy (PDT) research. While cyanines exhibit potential as photosensitizers (PSs) due to their large extinction coefficients and excellent biocompatibility, the inherent limitations in intersystem crossing severely affect therapeutic efficacy. Herein, we proposed a bottom-up magnetically enhanced photodynamic

Recently, the interest in nonbenzenoid hydrocarbons has resurged, focusing on the replacement of two benzenoid hexagons with a pentagon/heptagon pair, which has led to abundant azulenoid hydrocarbons. For ortho-fused benzenoid hydrocarbons with three or more rings, replacing the three hexagons with a set of two pentagons and one octagon is also possible. Following this concept, we designed pentacyclic

One hundred low-melting mixture solvents (LoMMSs) are utilized to systematically investigate the impact of acid–base regulation on the leaching efficiency of all-solid-state electrolytes. Results show that the acidity of LoMMSs is positively correlated with the Li leaching efficiency in the all-solid-state electrolytes aluminum-doped lithium lanthanum zirconium oxide and lithium lanthanum zirconium

A kinetic and thermodynamic tubular reactor model for the oxidative dehydrogenation of ethane using homogeneous NO/O2 mixtures is developed to investigate the factors controlling the ethylene selectivity. Two primary mechanisms for ethane oxidative dehydrogenation are identified from the model: the reaction between NO and NO2 to form OH radicals drives ethane dehydrogenation at large NO volume fractions

Manganese-based organic-inorganic metal halides (Mn-based OIMHs) scintillators have aroused a research upsurge due to their outstanding photoluminescence performance, low toxicity, and tunable structures. Herein, we demonstrate a molecular engineering strategy that synergistically enhances luminescence efficiency and radiation sensitivity by systematic elongation of branched alkyl chains in phosphonium-based

Harnessing sunlight for photocatalytic overall water splitting offers a sustainable approach to renewable hydrogen production, addressing global energy and environmental challenges. However, the development of efficient and durable photocatalysts remains a significant obstacle. This study introduces the design and performance of a 2D/2D Schottky heterojunction composed of Cu2[CuTCPP] MOF of nanometric

Membrane distillation (MD) is a promising separation technique for producing pure water from brine using low-grade heat. Covalent organic framework (COF) membranes with high porosity and well-ordered pore structure exhibit excellent flux and salt rejection during MD. However, long-term MD operation is often restricted by the inevitable gradual wetting of COF membranes which causes deterioration of

In this paper, we present a novel intracellular strategy for the in situ synthesis of gold–polymer nanocomposites within living bacteria. By transforming Escherichia coli into active nanofactories via intracellular polymerisation-induced self-assembly (iPISA), we achieved precise control over composite architecture. Our findings indicate that bacterial cells play an active role in constructing complex

Selective hydrogenation of alkynes to alkenes is pivotal in the chemical industry. Pd-containing materials have been proven to be effective catalysts, while balancing the activity-selectivity trade-off remains a significant challenge. Here we report the fabrication of Pd single atoms from the conversion of metal–organic polyhedra (MOPs) for the first time. The MOP (M6L4), constructed from Pd salt and

Strontium (Sr) is a primary radioactive substance that should be prioritized for removal from nuclear wastewater and hospital radioactive water. An efficient graphene oxide/hydroxyapatite adsorbent (GO/HAp) was investigated for the rapid adsorption of Sr2+. Herein, a kinetic and mechanism study of this system was implemented, and the morphology and structure of as-prepared composites were characterized

A novel approach is proposed for producing 4-ethylcyclohexanol, a versatile petrochemical in the polymer industry, from the renewable lignin in the presence of Cu–Ni/MgCrOx spinel catalysts. Under the synergistic effect between the Ni0, Cu,+ and the balanced acidic and basic properties of MgO and MgCr2O4, an exceptional yield of monomer (30.1?wt%) with 59.5% selectivity of 4-ethylcyclohexanol (yield

Catalytic amine–based solution regeneration has attracted considerable attention due to its potential to reduce energy consumption in carbon dioxide (CO2) separation. However, the limited catalytic activity and cycling stability of catalysts under high–temperature alkaline conditions hinder their industrial application. Herein, zirconium hydrogenphosphate (ZrHP) catalysts, featuring abundant acidic

The design and synthesis of robust catalysts is the key to improving CO2 conversion in the reverse-water gas shift (RWGS). In this article, the MoOx-C catalyst supported on AlOOH (xMoOx-C@AOH) is designed and synthesized by dielectric barrier discharge (DBD) plasma. The Mo-C bonds of the MoOx-C interface regulate the electronic structure of MoOx and promote the formation of oxygen vacancies. The catalyst

This study presents a low-cost, high-sensitivity glucose sensor (COL-MC) fabricated by integrating CuO-functionalized laser-induced graphene (LIG) with a capillary-driven microfluidic chip. The novel two-step synthesis eliminates noble metals, enhancing affordability while achieving a large surface area for superior sensitivity. The sensor demonstrates a linear response (R2?>?0.996) across 0.1–1.5?mmol/L

Stucco phase composition critically influences the mechanical properties of plasterboard, a cornerstone in modern construction. Traditional complete phase analysis (CPA) methods, while accurate, are hindered by prolonged processing times exceeding 12?h, impeding real-time quality control. This study introduces a machine learning-assisted CPA (ML-CPA) method leveraging artificial neural networks (ANNs)

Gas- non-spherical particle flow is constantly encountered in nature and industries, yet non-particle-scale simulation is hindered by the expensive computational cost. In the study, a computational-efficient coarse-grained superquadric DEM-CFD approach is developed for modelling gas–solid flow featuring non-spherical particle shape, reducing the number of non-spherical particles tracked and the resulting

Supramolecular polymers (SPs) driven by host-guest interactions have seen considerable advancements over the past decade, but the guest species involved are predominantly neutral molecules or cations. Strong and dependable macrocycle-anion interactions for supramolecular polymerization are highly sought after, yet the functionalities of this class of SPs featuring negatively charged backbones remain

Dysregulated lipid metabolism plays a critical role in the pathogenesis of numerous diseases. However, due to the lack of effective solutions, the dynamic monitoring and deep understanding of lipid metabolism in the progression of diseases has remained challenging. Herein, a polarity-sensitive, lipid droplets (LDs)-targeted probe was developed via molecular surgery for spatiotemporal super-resolution

Approximately 40% of marketed drugs exhibit suboptimal pharmacokinetic profiles. Co-crystallization, where pairs of molecules form a multicomponent crystal, constitutes a promising strategy to enhance physicochemical properties without compromising pharmacological activity. However, finding promising co-crystal pairs is resource-intensive, due to the large and diverse range of possible molecular combinations

Scintillators featuring bright and fast-response properties are essential for high-speed and dynamic X-ray imaging. Nevertheless, simultaneously possessing high light yields and fast response remains a significant challenge for most scintillators. Herein, we propose a strategy to achieve the bright and fast-response characteristics of scintillators by leveraging the combined effects of dielectric and

Aqueous Zn-ion batteries (AZIBs) are widely regarded as the ideal candidate for large-scale energy storage systems. However, Zn metal anode has long faced challenges, such as: hydrogen evolution reaction, dendrite growth, surface corrosion. Herein, we report the development of a self-healable and strongly adhesive polymer protective layer for AZIBs, which is achieved by polymerizing a natural small

The development of closed-loop recyclable polymers with comparable performances with commodity plastics remains as a challenge to establish a circular plastic economy. In this contribution, we propose a?precipitation/crystallization driven non-equilibrium ring-opening polymerization of δ-thiovalerolactone (δTVL) to produce high-molecular-weight PTVL in the presence of a strong base/urea binary catalyst

Photocatalysis provides a promising approach to produce green energy, by which the intermittent solar energy can be converted into storable chemical energy. Well-known that the electron transfer rate has great influence on the photocatalytic efficiency. Revealing the influence of electron transfer rate on the photocatalytic efficiency from a molecular level is of great significance but challenge. Herein

Site-selective and divergent functionalizations on saturated alkyl chain at specific unfunctionalized positions is a key challenge in organic chemistry and other related areas and offers unprecedented synthetic opportunities. Herein, a ligand-controlled Ni-catalyzed site-selective and divergent alkyl-alkyl reductive coupling between two different alkyl halides has been developed. Notably, the reaction

Pancreatic cancer (PC) remains difficult to treat due to its dense extracellular matrix (ECM), immunosuppressive tumor microenvironment (TME), and deep-seated anatomy. To address these challenges, we developed IR&ZnPc@LNP-NO, an ultrasound (US)-responsive lipid nanosonosensitizer that synergizes sonodynamic therapy (SDT), chemotherapy, and immunotherapy for orthotopic PC. IR&ZnPc@LNP-NO undergoes three

This work reports the optimization strategy for the design of a microfluidic platform to achieve the separation and recovery of aqueous mixtures of rare earth elements (REEs); the work showcases the separation of dysprosium, neodymium and lanthanum using microextraction modules with an organic phase constituted of Cyanex? 572 diluted in Shellsol? D70. An optimization model has been developed to assist

Surfactants play a crucial role in the removal of oil from solids during the treatment of oily sludge by facilitating the formation of oil-in-water emulsions. However, to effectively destabilize and break these emulsions, a secondary surfactant or demulsifier with distinct interfacial properties is often required. Achieving efficient separation of both oil–solid and oil–water phases using a single